MarketGrader Developed Markets (ex-Australia) Health Care Index


Five Largest Companies (Top 5 of 39)
Symbol Name Grade Market Cap Country
JNJ Johnson & Johnson 63.8 $465,600.00 US
PFE Pfizer Inc. 86.9 $284,248.00 US
ABBV AbbVie, Inc. 64.4 $269,467.00 US
NOVO.B.DK Novo Nordisk A/S Class B 71.3 $245,110.48 DK
MRK Merck & Co., Inc. 82.9 $232,372.00 US

Five Smallest Companies (Top 5 of 11)
Symbol Name Grade Market Cap Country
TECN.CH Tecan Group AG 45.2 $3,805.45 CH
7747.JP Asahi Intecc Co., Ltd. 45.7 $4,089.23 JP
CRSP CRISPR Therapeutics AG 68.3 $4,901.49 CH
BANB.CH Bachem Holding AG Class B 57.9 $5,587.30 CH
HALO Halozyme Therapeutics, Inc. 81.5 $6,315.35 US

Companies with Most Selections Among Current Components
Symbol Name Grade Times* Country
NOVO.B.DK Novo Nordisk A/S Class B 71.3 30 DK
WAT Waters Corporation 69.2 25 US
JNJ Johnson & Johnson 63.8 21 US
REGN Regeneron Pharmaceuticals, Inc. 80.2 18 US
BMY Bristol-Myers Squibb Company 53.2 16 US
ALGN Align Technology, Inc. 59.8 15 US
1177.HK Sino Biopharmaceutical Limited 79.3 15 HK
SOON.CH Sonova Holding AG 60.5 15 CH
STMN.CH Straumann Holding AG 66.5 13 CH
4519.JP Chugai Pharmaceutical Co., Ltd. 85.7 13 JP
*Number of times selected at Index semi-annual reconstitutions since inception date.
Index Bio
Average Market Cap $63,689.91
Median Market Cap $17,828.50
Avg. 3 Mo. Dollar Vol. $258,377,901.19
Avg. 3 Mo. Trading Vol. 3,759,000
Last Rebalance Date 03/21/2022
Companies Replaced 17
Biggest Industry Increase Pharmaceuticals: Major
Biggest Industry Decrease Medical Specialties

Fundamental Attributes
Trailing P/E Ratio (12 Mo.) 22.69
Forward P/E Ratio (12 Mo.) 22.84
Price/Book Ratio 4.68
Avg. Revenue Chg. - 3 Yr 59.42%
Avg. Op. Income Chg. - 3 Yr. 100.0%
Avg. EPS Growth - 3 Yr. 24.24%
Avg. EPS Growth - 1 Yr. 24.12%
Avg. Operating Margin 25.69%
Avg. LT Debt to Total Capital 25.48%
Avg. Return on Equity 24.65%
Dividend Yield 0.42%
Index Average Grade
MarketGrader Developed Markets (ex-Australia) Health Care Index 67.25
Country Breakdown
United States Of America 52.0%
Switzerland 12.0%
France 6.0%
Japan 6.0%
Korea, Republic Of 4.0%
Italy 4.0%
Hong Kong 4.0%
Ireland 2.0%
Luxembourg 2.0%
New Zealand 2.0%
Germany 2.0%
Belgium 2.0%
Denmark 2.0%


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